USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: DDAH1_HUMAN USC-OGP 2-DE database:  DDAH1_HUMAN DDAH1_HUMAN General information about the entry View entry in simple text format Entry name DDAH1_HUMAN Primary accession number O94760 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Short=DDAH-1; Short=Dimethylarginine dimethylaminohydrolase 1; EC=3.5.3.18; AltName: Full=DDAHI; AltName: Full=Dimethylargininase-1;. Gene name Name=DDAH1 Synonyms=DDAH Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1205: pI=5.50; Mw=38683 SPOT OGP-1209: pI=5.53; Mw=37929 Cross-references UniProtKB/Swiss-Prot O94760; DDAH1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name DDAH1_HUMAN Primary accession number O94760 Secondary accession number(s) Q5HYC8 Q86XK5 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 156) Name and origin of the protein Description RecName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Short=DDAH-1; Short=Dimethylarginine dimethylaminohydrolase 1; EC=3.5.3.18; AltName: Full=DDAHI; AltName: Full=Dimethylargininase-1; Gene name Name=DDAH1 Synonyms=DDAH Encoded on Name=DDAH1; Synonyms=DDAH Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Hydrolase; Metal-binding; Reference proteome; S-nitrosylation; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AB001915; BAA37117.1; -; mRNA EMBL BX648145; CAI45988.1; -; mRNA EMBL AC092807; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AL078459; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AL360219; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471097; EAW73199.1; -; Genomic_DNA EMBL BC033680; AAH33680.1; -; mRNA EMBL BC043235; AAH43235.2; -; mRNA CCDS CCDS44170.1; -. [O94760-2]; . CCDS CCDS705.1; -. [O94760-1]; . RefSeq NP_001127917.1; NM_001134445.1. [O94760-2]; . RefSeq NP_036269.1; NM_012137.3. [O94760-1]; . RefSeq XP_005270767.1; XM_005270710.2. [O94760-2]; . UniGene Hs.713411; -; . PDB 2JAI; X-ray; 2.30 A; A/B=2-285 PDB 2JAJ; X-ray; 2.00 A; A/B=2-285 PDB 3I2E; X-ray; 2.03 A; A/B=1-285 PDB 3I4A; X-ray; 1.90 A; A/B=1-285 PDB 3P8E; X-ray; 2.49 A; A/B=1-285 PDB 3P8P; X-ray; 2.50 A; A/B=1-285 PDBsum 2JAI; -; . PDBsum 2JAJ; -; . PDBsum 3I2E; -; . PDBsum 3I4A; -; . PDBsum 3P8E; -; . PDBsum 3P8P; -; . ProteinModelPortal O94760; -; . SMR O94760; -; . BioGrid 117114; 14; . DIP DIP-61582N; -; . IntAct O94760; 2; . STRING 9606.ENSP00000284031; -; . BindingDB O94760; -; . ChEMBL CHEMBL6036; -; . DrugBank DB00155; L-Citrulline; . GuidetoPHARMACOLOGY 1247; -; . iPTMnet O94760; -; . PhosphoSitePlus O94760; -; . SwissPalm O94760; -; . BioMuta DDAH1; -; . REPRODUCTION-2DPAGE IPI00220342; -; . EPD O94760; -; . MaxQB O94760; -; . PaxDb O94760; -; . PeptideAtlas O94760; -; . PRIDE O94760; -; . Ensembl ENST00000284031; ENSP00000284031; ENSG00000153904. [O94760-1]; . Ensembl ENST00000426972; ENSP00000411189; ENSG00000153904. [O94760-2]; . Ensembl ENST00000535924; ENSP00000439045; ENSG00000153904. [O94760-2]; . Ensembl ENST00000539042; ENSP00000438604; ENSG00000153904. [O94760-1]; . GeneID 23576; -; . KEGG hsa:23576; -; . UCSC uc001dlb.4; human. [O94760-1]; . CTD 23576; -; . DisGeNET 23576; -; . GeneCards DDAH1; -; . HGNC HGNC:2715; DDAH1; . HPA HPA006308; -; . MIM 604743; gene; . neXtProt NX_O94760; -; . OpenTargets ENSG00000153904; -; . PharmGKB PA27185; -; . eggNOG ENOG410IFS6; Eukaryota; . eggNOG COG1834; LUCA; . GeneTree ENSGT00390000009331; -; . HOGENOM HOG000161035; -; . HOVERGEN HBG055937; -; . InParanoid O94760; -; . KO K01482; -; . OMA CNGIALI; -; . OrthoDB EOG091G0M5S; -; . PhylomeDB O94760; -; . TreeFam TF314737; -; . BRENDA 3.5.3.18; 2681; . Reactome R-HSA-203615; eNOS activation; . ChiTaRS DDAH1; human; . EvolutionaryTrace O94760; -; . GenomeRNAi 23576; -; . PRO PR:O94760; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000153904; -; . CleanEx HS_DDAH1; -; . ExpressionAtlas O94760; baseline and differential; . Genevisible O94760; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0016597; F:amino acid binding; IEA:Ensembl; . GO GO:0003824; F:catalytic activity; TAS:ProtInc; . GO GO:0016403; F:dimethylargininase activity; IDA:UniProtKB; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0006527; P:arginine catabolic process; TAS:ProtInc; . GO GO:0000052; P:citrulline metabolic process; IDA:UniProtKB; . GO GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc; . GO GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl; . GO GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:BHF-UCL; . GO GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome; . GO GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL; . InterPro IPR033199; DDAH/AD; . InterPro IPR033197; DDAH1; . PANTHER PTHR12737; PTHR12737; 1; . PANTHER PTHR12737:SF25; PTHR12737:SF25; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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